Hereditary multiple exostoses
Hereditary disorder transmitted by autosomal dominant genes (EXT1-3) and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.
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Fortis Anandapur
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Peerless Hospital and B.K Roy Research Centre
DNB Orthopaedic Surgery, IMRCS
Portea Medical
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Ndta Neuro Developmental Treatment Association
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Guru Nanak Dev University
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Krishna Institute of Medical Sciences (KIMS)
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Center of Medical Genetics, Sir Ganga Ram Hospital
PhD Human Genetics
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