Hypodontia

A rare genetic disorder with an autosomal dominant pattern of inheritance. It is associated with mutations in the MSX-1 gene on chromosome 4 which alter ectodermal morphogenesis. Characteristic clinical signs include absent or poorly-formed dentition and brittle, spoon-shaped finger and toenails. Clinical course features an increased incidence of dental caries but is essentially benign.

Disease Alternative Name

hypodontia with nail dysplasia

hnd

hypodontia-nail dysplasia

witkop syndrome

hypodontia and nail dysplasia

tooth and nail syndrome

MainRecentTopDoctors

Recent Cases of Hypodontia

Browse recently discussed Hypodontia cases by specialists

Dr. Rohit Valecha

Dentistry

A 10 year old child presented for a dental assessment as parents are concerned for his dental condition. Typical peg-sha...See More

224 Views

, 2 Likes

, 5 Answers

LikeAnswers Share

5 Answers2 Likes

Dr. Tamil Venthan

General Practice

Father brought his 9 year old son with gait difficulties who is a known case of SPASTIC ATAXIC SYNDROME DUE TO LEUKOENCEPHALOPATHY/ hypogonadotropic hypogonadism, diagnosed at the age of 2 years. Before 2 years all the milestones were achi...See More

271 Views

, 1 Answer

LikeAnswers Share

1 Answer0 Like

See more recent cases